Abstract: The geomorphochronological approaches are believed to have important implications for the 1:250 000 regional geological survey of the Qinghai-Xizang Plateau because of complicated features of the Plateau uplift and denudation, and foul weather and geographic conditions. The geomorphological features are technologically significant in that they may provide plenty of important informations about the Plateau uplift, environmental evolution and neotectonism, and assist in the reconstruction of the timing and evolution of geological processes. The present paper focuses the significance and method of the geomorphochronological approaches of the Qinghai-Xizang Plateau in the 1:250 000 regional geological survey. The spatial relations among distinctive geomorphological features should be ascertained in the field geological survey, and the samples should be sampled from the localities suitable for the geomorphochronological approaches. The results of research in the study show that the geomorphochronological approaches are effective for the examination of the Plateau uplift and environmental evolution.