Abstract: The spectacular changes on a global scale once took place during the latest Permian. These events include palaeomagnetic reversal,palaeoclimatic changes,large-scale regression,anoxic events,volcanism,geochemical anomaly,and mass extinction during the periods of the Phanerozoic. The discovery of the meteorite falls (micropellets) and Ir anomaly at the Permian/Triassic boundary on a global scale show that the astronomical events such as meteorite impacts also occurred during the latest Permian,followed by the breakup of Pangea from the earliest Triassic (250 Ma). The breakup in reality marked the waning and waxing of the Tethys Sea,or the plate convergence around the Tethys Sea. The meteorite impact sites may be delineated in the northern par of the latest Permian Tethys Sea. The meteorite impacts eventually resulted in the termination of the Tethys Sea and the breakup of Pangea.